Scientists increase the solubility of an effective antidepressant by a factor of 1,600

Scientists increase the solubility of an effective antidepressant by a factor of 1,600
PromData – агенство промышленных и ценовых данных
22.01.2024
The anti-anxiety drug diazepam causes side effects: drowsiness, confusion, and nausea. The same applies to the antidepressant amitriptyline. A possible solution to the problem could be a new compound, GML-3. It simultaneously exhibits the anti-anxiety activity of diazepam and the antidepressant activity of amitriptyline. At the same time, it is devoid of most of their side effects. However, it is not used in pharmaceuticals since it is poorly soluble in water; this is a necessary condition to create convenient dosage forms based on the drug.

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